Description

5-(Azidomethyl)Uridine is a modified nucleoside analog featuring an azidomethyl group at the 5-position of the uracil base. This functionalization makes it a versatile and critical building block for click chemistry applications, particularly in the synthesis of oligonucleotide probes and bioconjugates. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic assay design.

Application

• Click Chemistry Reagent: Key intermediate for Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to label biomolecules.
• Oligonucleotide Synthesis: Incorporation into DNA/RNA strands for post-synthetic modification, enabling fluorescent tagging or attachment of other functional groups.
• Bioconjugation: Facile conjugation of nucleic acids to proteins, peptides, surfaces, or nanoparticles for diagnostic and therapeutic platforms.
• Chemical Biology Probes: Synthesis of activity-based probes to study enzyme function or cellular processes.
• Antiviral Research: As a modified nucleoside precursor in the development of novel antiviral agents.
• Materials Science: Functionalization of polymers or surfaces with nucleic acid motifs for biosensor development.

Basic Information

Product Name	5-(Azidomethyl)Uridine
CAS No.	24751-67-5
Molecular Formula	C10H13N5O6
Molecular Weight	299.24 g/mol
Synonyms	5-Azidomethyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-(azidomethyl)pyrimidine-2,4-dione; 5-(Azidomethyl)-1-β-D-ribofuranosyluracil; N1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(azidomethyl)pyrimidine-2,4(1H,3H)-dione; 5-N3mdUrd
EINECS	Contact for details

Quality Control

Our 5-(Azidomethyl)Uridine is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal quality standards to guarantee reliable performance in your click chemistry and bioconjugation workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.