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o-(1,1-Dimethylethyl)-n-[(Benzyloxy)Carbonyl]-L-Tyrosine Pentachlorophenyl Ester CAS NO 24735-61-3
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CAS No.:24735-61-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
o-(1,1-Dimethylethyl)-n-[(Benzyloxy)Carbonyl]-L-Tyrosine Pentachlorophenyl Ester is a specialized, high-purity protected amino acid derivative designed for advanced organic synthesis. This compound serves as a critical building block, enabling the controlled formation of peptide bonds while protecting sensitive functional groups from unwanted side reactions. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel peptides, peptidomimetics, and other bioactive molecules.
Application
- Solid-Phase Peptide Synthesis (SPPS): A key reagent for the controlled, sequential coupling of amino acids in automated peptide synthesizers.
- Solution-Phase Peptide Synthesis: Used in classical solution-phase methods for constructing complex peptide sequences and cyclic peptides.
- Peptidomimetic Research: Acts as a precursor for creating non-natural amino acid analogs and peptide-like molecules with enhanced stability or biological activity.
- Pharmaceutical Intermediate: Employed in the research and development stages of new therapeutic peptides and protein-based drugs.
- Bioconjugation Chemistry: Useful for attaching peptide sequences to other molecules, surfaces, or carriers in biotech applications.
- Academic & Industrial R&D: A valuable tool for chemists in universities and contract research organizations (CROs) exploring new synthetic methodologies.
Basic Information
| Product Name | o-(1,1-Dimethylethyl)-n-[(Benzyloxy)Carbonyl]-L-Tyrosine Pentachlorophenyl Ester |
| CAS No. | 24735-61-3 |
| Molecular Formula | C29H28Cl5NO5 |
| Molecular Weight | 643.80 g/mol |
| Synonyms | Boc-Tyr(Bzl)-OPcp; Boc-L-Tyrosine(Bzl)-OPcp Ester; N-tert-Butoxycarbonyl-O-benzyl-L-tyrosine pentachlorophenyl ester; (2S)-3-(4-Benzyloxyphenyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid pentachlorophenyl ester; Boc-Tyr(Bzl)-OPentachlorophenyl; L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-, pentachlorophenyl ester; Protected L-Tyrosine PCP Ester |
| EINECS | Contact for details |
Quality Control
Our o-(1,1-Dimethylethyl)-n-[(Benzyloxy)Carbonyl]-L-Tyrosine Pentachlorophenyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Optical Rotation | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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