Description

Trimethylsilyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Mannopyranoside is a highly functionalized, fully silylated derivative of D-mannose, designed for advanced synthetic applications. This compound is a critical intermediate for the protection and controlled manipulation of carbohydrate hydroxyl groups, enabling precise chemical transformations. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex glycoconjugates, nucleosides, and other bioactive molecules.

Application

• Glycoconjugate Synthesis: A key protected intermediate for the preparation of complex oligosaccharides, glycopeptides, and glycolipids.
• Nucleoside & Nucleotide Chemistry: Used in the synthesis of modified nucleosides and nucleotides, where selective deprotection of silyl groups is required.
• Pharmaceutical Intermediate: Serves as a building block in the research and development of antiviral, anticancer, and other therapeutic agents.
• Agrochemical Synthesis: Employed in the creation of novel carbohydrate-based active ingredients and adjuvants.
• Chemical Biology Probes: Useful for the synthesis of labeled carbohydrate probes for studying biological recognition and signaling pathways.
• Chiral Pool Synthesis: Provides a versatile chiral template for the asymmetric synthesis of non-carbohydrate targets.

Basic Information

Product Name	Trimethylsilyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Mannopyranoside
CAS No.	24707-99-1
Molecular Formula	C21H52O6Si5
Molecular Weight	569.08 g/mol
Synonyms	Per-O-trimethylsilyl-α-D-mannopyranoside; α-D-Mannopyranoside, 2,3,4,6-tetrakis-O-(trimethylsilyl)-, trimethylsilyl ether; 1-O-Trimethylsilyl-2,3,4,6-tetra-O-trimethylsilyl-α-D-mannopyranoside; Fully Silylated α-D-Mannose; α-D-Mannose Penta-TMS Derivative; TMS-α-D-Mannopyranoside, per-O-TMS; 24707-99-1; α-D-Mannopyranoside, 2,3,4,6-tetrakis-O-(trimethylsilyl)-, 1-(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our Trimethylsilyl 2-O,3-O,4-O,6-o-Tetrakis(Trimethylsilyl)-α-D-Mannopyranoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C), HPLC, and GC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.