Description

(2S,4R)-n-[2-Chloro-1-[(2R,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-Methylsulfanyl-Oxan-2-Yl]Propyl]-1-Methyl-4-Propyl-Pyrrolidine-2-Carboxamide is a complex, high-purity chiral compound with significant potential in advanced pharmaceutical research and development. Its intricate molecular architecture, featuring a modified sugar moiety (methylsulfanyl-oxane) linked to a substituted pyrrolidine carboxamide, makes it a valuable building block or intermediate for synthesizing novel therapeutic agents. This compound is primarily targeted at pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drugs, particularly in areas requiring sophisticated stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of new active pharmaceutical ingredients (APIs), especially for complex target molecules.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Glycomimetic Drug Development: The thiomethyl sugar component makes it relevant for developing glycomimetics, which mimic carbohydrates for therapeutic applications in areas like antiviral or anticancer research.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of candidate drugs under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Can be utilized to create specialized probes for studying biological pathways and enzyme interactions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item	Details
Product Name	(2S,4R)-n-[2-Chloro-1-[(2R,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-Methylsulfanyl-Oxan-2-Yl]Propyl]-1-Methyl-4-Propyl-Pyrrolidine-2-Carboxamide
CAS No.	24696-19-3
Molecular Formula	C18H33ClN2O5S
Molecular Weight	424.98 g/mol
Synonyms	1-Methyl-4-propyl-N-[(1S)-2-chloro-1-[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl]propyl]pyrrolidine-2-carboxamide; (2S,4R)-1-Methyl-4-propyl-N-[(1S)-2-chloro-1-[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl]propyl]pyrrolidine-2-carboxamide; Pyrrolidine-2-carboxamide derivative with thiomethyl hexose; Chiral pyrrolidine glycoside intermediate; CAS 24696-19-3.
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the integrity of our advanced intermediates. Production of this chiral compound is supported by comprehensive analytical characterization, including HPLC, chiral HPLC, NMR, and MS, to verify identity, stereochemical purity, and chemical purity. A detailed Certificate of Analysis (COA) is provided with each batch, documenting critical specifications. Our commitment to quality supports compliance with the stringent requirements of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.