Description

Fluoro 2-Deoxy-2-Fluoro-3,4,6-Tri-o-Acetyl-D-Mannopyranoside is a key fluorinated carbohydrate intermediate, specifically a protected mannose derivative. This compound is essential for the synthesis of complex fluorinated sugars and nucleoside analogs used in pharmaceutical research and development. It is primarily required by research institutions and pharmaceutical companies engaged in the development of antiviral agents, diagnostic imaging probes, and other bioactive molecules where fluorine substitution is critical for metabolic stability and binding affinity.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of fluorinated nucleoside analogs with potential antiviral and anticancer activity.
• Probe Development: Used in the preparation of 18F-labeled compounds for Positron Emission Tomography (PET) imaging agents.
• Glycochemistry Research: Serves as a versatile precursor for constructing complex, fluorinated oligosaccharides to study carbohydrate-protein interactions.
• Medicinal Chemistry: Enables the introduction of fluorine atoms into lead compounds to optimize pharmacokinetic properties such as metabolic stability and membrane permeability.
• Process Chemistry: Used in scale-up synthesis for the production of active pharmaceutical ingredients (APIs) containing fluorinated sugar moieties.

Basic Information

Product Name	Fluoro 2-Deoxy-2-Fluoro-3,4,6-Tri-o-Acetyl-D-Mannopyranoside
CAS No.	24679-92-3
Molecular Formula	C12H16FO8
Molecular Weight	307.25 g/mol
Synonyms	2-Deoxy-2-fluoro-3,4,6-tri-O-acetyl-α-D-mannopyranosyl Fluoride; 2-Fluoro-2-deoxy-3,4,6-tri-O-acetyl-α-D-mannopyranosyl Fluoride; 3,4,6-Tri-O-acetyl-2-deoxy-2-fluoro-α-D-mannopyranosyl Fluoride; α-D-Mannopyranosyl Fluoride, 2-deoxy-2-fluoro-3,4,6-tri-O-acetyl-; 24679-92-3; Fluorinated Triacetyl Mannose Derivative
EINECS	Contact for details

Quality Control

Our Fluoro 2-Deoxy-2-Fluoro-3,4,6-Tri-o-Acetyl-D-Mannopyranoside is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and process development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.