Description

Pivalic Acid Trityl Ester is a specialized organic compound used as a versatile protecting group reagent in advanced synthetic chemistry. Its primary value lies in its ability to selectively protect carboxylic acid functionalities under mild conditions, which is critical for the multi-step synthesis of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for protecting sensitive carboxyl groups during complex reaction sequences.
• Peptide Synthesis: Employed as a protecting reagent for glutamic and aspartic acid side chains in solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Used in the development and scale-up of novel herbicides, fungicides, and plant growth regulators requiring selective protection strategies.
• Fine Chemical Production: Facilitates the synthesis of specialty chemicals, flavors, fragrances, and advanced materials where precise molecular architecture is required.
• Academic & Process R&D: A valuable tool for methodological development in organic synthesis and for exploring new catalytic processes in laboratory settings.

Basic Information

Product Name	Pivalic Acid Trityl Ester
CAS No.	24523-65-7
Molecular Formula	C26H26O2
Molecular Weight	370.49 g/mol
Synonyms	2,2-Dimethylpropanoic Acid Triphenylmethyl Ester; Pivaloyloxytriphenylmethane; Trityl Pivalate; Triphenylmethyl Pivalate; Piv-O-Trt; PivOTr; (Triphenylmethyl) 2,2-dimethylpropanoate; 2,2-Dimethylpropionic Acid Trityl Ester
EINECS	Contact for details

Quality Control

Our Pivalic Acid Trityl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles via techniques such as HPLC, NMR, and GC. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.