Description

tert-Butyl 2-Bromobutyrate CAS NO 24457-21-4 is a versatile brominated ester building block, primarily used as an intermediate in advanced organic synthesis. Its value lies in the reactive bromine atom and the acid-labile tert-butyl ester group, which facilitate controlled chemical transformations and serve as a protective group. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring the introduction of a butyric acid derivative.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that utilize halogenated ester motifs.
• Organic Synthesis Reagent: Serves as an alkylating agent or a precursor for generating nucleophilic species in cross-coupling reactions (e.g., Grignard or Reformatsky-type reactions).
• Peptide Mimetics & Prodrug Development: The tert-butyl ester group is a common protecting group in peptide chemistry and can be used to create prodrug forms of carboxylic acid-containing drugs.
• Material Science Research: Employed as a monomer or modifying agent in the development of specialized polymers and functional materials.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	tert-Butyl 2-Bromobutyrate
CAS No.	24457-21-4
Molecular Formula	C8H15BrO2
Molecular Weight	223.11 g/mol
Synonyms	2-Bromobutyric Acid tert-Butyl Ester; Butanoic acid, 2-bromo-, 1,1-dimethylethyl ester; tert-Butyl α-bromobutyrate; 1,1-Dimethylethyl 2-bromobutanoate; 2-Bromobutanoic Acid tert-Butyl Ester; t-Butyl 2-bromobutyrate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromobutyrate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.