Description

17-Ethinyl-3,17-Dihydroxy-18-Methylestra-2,5(10)-Diene3-Methylether is a high-purity synthetic steroid derivative, also known as 18-Methylnorethisterone 3-Methyl Ether. This compound is a key advanced pharmaceutical intermediate valued for its role in the synthesis of potent hormonal APIs. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of steroidal drugs. Our supply ensures consistent quality and reliable availability for critical R&D and commercial-scale synthesis projects.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel progestins and other steroidal active pharmaceutical ingredients (APIs).
• Hormone Research: Used in biochemical and pharmacological research to study structure-activity relationships (SAR) of steroidal compounds.
• Contraceptive Development: Serves as a precursor in the development of next-generation hormonal contraceptives.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Utilized in route scouting and optimization for the industrial-scale manufacturing of complex steroid molecules.

Basic Information

Item	Details
Product Name	17-Ethinyl-3,17-Dihydroxy-18-Methylestra-2,5(10)-Diene3-Methylether
CAS No.	24377-29-5
Molecular Formula	C23H30O3
Molecular Weight	354.49 g/mol
Synonyms	18-Methylnorethisterone 3-Methyl Ether; 18-Methyl Norethindrone 3-Methyl Ether; 17α-Ethynyl-17β-hydroxy-18-methylestra-4,9-dien-3-one 3-methyl ether; 18-Methyl-19-nor-17α-pregn-4-en-20-yn-3-one, 17β-ol, 3-methyl ether; Lynestrenol 3-Methyl Ether; Org 2969 3-Methyl Ether
EINECS	Contact for details

Quality Control

Our 17-Ethinyl-3,17-Dihydroxy-18-Methylestra-2,5(10)-Diene3-Methylether is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using a desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.