Description

L-Adrenaline Bitartrate is the bitartrate salt form of the naturally occurring catecholamine and neurotransmitter, L-Epinephrine. This high-purity active pharmaceutical ingredient (API) is critical for its potent vasoconstrictive, bronchodilatory, and cardiac stimulant properties. It is an essential raw material for the formulation of emergency medications, ophthalmic solutions, and advanced pharmaceutical research, serving the needs of global pharmaceutical manufacturers, compounding pharmacies, and biotechnology research institutions.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for the emergency treatment of severe allergic reactions (anaphylaxis), cardiac arrest, and acute asthma attacks.
• Ophthalmic Solutions: Key component in eye drops used to manage open-angle glaucoma and for pupil dilation during ophthalmic surgery.
• Local Anesthetic Adjuvant: Added to local anesthetics (e.g., in dental procedures) to prolong their effect by causing vasoconstriction at the site of injection.
• Cardiovascular Research: Vital reference standard and tool in preclinical and clinical research studying adrenergic receptors, cardiac function, and autonomic nervous system responses.
• Veterinary Medicine: Used in emergency kits and surgical procedures for animals, addressing similar critical conditions as in human medicine.
• Diagnostic Reagent: Employed in *in vitro* diagnostic kits and biochemical assays for research and clinical testing purposes.

Basic Information

Product Name	L-Adrenaline Bitartrate
CAS No.	24351-82-4
Molecular Formula	C9H13NO3 • C4H6O6
Molecular Weight	333.30 g/mol
Synonyms	(-)-Epinephrine Bitartrate; L-Epinephrine Bitartrate; Adrenaline Acid Tartrate; (R)-(-)-Adrenaline Bitartrate; 1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol Bitartrate; Levorenin Bitartrate; Suprarenin Bitartrate; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol (R)-Bitartrate
EINECS	246-203-6

Quality Control

Our L-Adrenaline Bitartrate is manufactured and tested under strict quality management systems. It meets exacting standards for pharmaceutical-grade active ingredients, with specifications aligned to major pharmacopoeias such as USP and EP. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring full traceability and compliance for GMP-driven applications.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C (59-77°F). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). The container must be kept tightly sealed in a dry environment to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	-50.0° to -53.5° (c = 2 in water)
pH (5% solution)	3.0 - 4.0
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.