Description

3,3-Dimethylbut-1-Ylisocyanide is a versatile and highly reactive organic building block, specifically an isocyanide derivative. Its primary value lies in its role as a critical reagent in multi-component reactions, enabling the efficient synthesis of complex heterocyclic and peptidomimetic structures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it facilitates the creation of novel molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the Ugi and Passerini multi-component reactions for the rapid generation of compound libraries and drug-like molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides through the construction of complex nitrogen-containing heterocycles.
• Material Science Research: Employed in the synthesis of functional polymers and ligands for catalysis, leveraging its unique reactivity.
• Peptidomimetics & Medicinal Chemistry: Facilitates the isonitrile-based synthesis of peptide analogs and other bioactive compounds.
• Academic & Industrial R&D: Serves as a fundamental reagent for methodological development in organic synthesis and chemical biology.

Basic Information

Product Name	3,3-Dimethylbut-1-Ylisocyanide
CAS No.	24313-59-5
Molecular Formula	C7H11N
Molecular Weight	109.17 g/mol
Synonyms	1-Isocyano-3,3-dimethylbutane; 3,3-Dimethylbutyl isocyanide; 3,3-Dimethylbutyl isonitrile; (3,3-Dimethylbutyl)isocyanide; tert-Butylmethyl isocyanide; NSC 163045; 3,3-Dimethyl-1-isocyanobutane
EINECS	Contact for details

Quality Control

Our 3,3-Dimethylbut-1-Ylisocyanide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including purity assay and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C. Due to its sensitivity, allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.