Description

(3Ar,6S)-3,3A,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-4α-Hydroxy-9-Methyl-3-Methylenespiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-2-One is a complex, high-purity spirocyclic organic compound characterized by its unique azulene-fused furan and oxirane ring system. This compound matters as a sophisticated chemical intermediate and building block for advanced synthetic chemistry, offering a rigid, polycyclic framework for constructing novel molecular architectures. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for complex natural product analogs.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its complex spirocyclic structure for bioactivity.
• Organic Synthesis Reagent: Acts as a versatile precursor for synthesizing other complex spiro and polycyclic compounds in academic and industrial R&D.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific optical or electronic properties.
• Catalyst Ligand Development: Its defined stereochemistry and functional groups make it a candidate for developing novel asymmetric catalysts.

Basic Information

Product Name	(3Ar,6S)-3,3A,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-4α-Hydroxy-9-Methyl-3-Methylenespiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-2-One
CAS No.	24268-44-8
Molecular Formula	C₁₅H₁₈O₄
Molecular Weight	262.30 g/mol
Synonyms	Spiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-2-one, octahydro-4α-hydroxy-9-methyl-3-methylene-, (3aR,6S,6aS,9aR,9bS)-rel-; (3aR,6S,6aS,9aR,9bS)-Octahydro-4α-hydroxy-9-methyl-3-methylenespiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-2-one; Azuleno-fused spirooxirane lactone; CAS 24268-44-8; 4α-Hydroxy-9-methyl-3-methylenespiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-2-one
EINECS	Contact for details

Quality Control

Our (3Ar,6S)-3,3A,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-4α-Hydroxy-9-Methyl-3-Methylenespiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-2-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.