Description

Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Trans,trans- (8Ci) is a complex, stereochemically defined spirocyclic organic compound featuring a fused naphthalene-oxazolidinone structure. This specific molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and a key building block in organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and fine chemical industries for the construction of novel active molecules, particularly in areas requiring rigid, three-dimensional scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of novel drug candidates, especially those targeting the central nervous system or requiring complex heterocyclic frameworks.
• Organic Synthesis Reagent: Used in advanced organic chemistry research for constructing complex spirocyclic and polycyclic compounds due to its defined stereochemistry and functional groups.
• Agrochemical Research: Employed in the development of new generation pesticides and herbicides where its unique structure can contribute to specific biological activity.
• Material Science Precursor: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & Industrial R&D: A key compound for methodological studies in asymmetric synthesis, catalysis, and the development of new synthetic routes.

Basic Information

Item	Detail
Product Name	Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Trans,trans- (8Ci)
CAS No.	24192-12-9
Molecular Formula	C₁₄H₂₁NO₂
Molecular Weight	235.33 g/mol
Synonyms	Octahydrospiro[naphthalene-2(1H),5'-oxazolidin]-2'-one, trans,trans-; Spiro(1,3-oxazolidine-5,2'-(1',2',3',4'-tetrahydro)naphthalene)-2-one, octahydro-, trans,trans-; (3aR,4S,7aS,8R)-Octahydrospiro[naphthalene-2(1H),5'-oxazolidin]-2'-one; trans,trans-Octahydrospiro[naphthalene-2(1H),5-oxazolidin]-2-one; 24192-12-9
EINECS	Contact for details

Quality Control

We supply Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Trans,trans- (8Ci) in high-purity grades suitable for demanding research and development applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans,trans isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.