Description

Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Trans,cis- (8Ci) is a complex, high-purity spirocyclic organic compound with the CAS number 24192-11-8. This specialized chemical serves as a critical advanced intermediate or building block in sophisticated organic synthesis, enabling the construction of novel molecular architectures. It is primarily required by pharmaceutical R&D and fine chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Synthesis: Used in the development of advanced, high-efficacy pesticides and herbicides with complex stereochemistry.
• Material Science Research: Serves as a precursor for creating specialized polymers or liquid crystals with unique optical or electronic properties.
• Asymmetric Catalysis: Potential use as a ligand or core structure in designing chiral catalysts for enantioselective synthesis.
• Academic & Industrial R&D: Employed in chemical research to explore new reaction pathways and synthesize complex natural product analogs.

Basic Information

Product Name	Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Trans,cis- (8Ci)
CAS No.	24192-11-8
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27 g/mol
Synonyms	Octahydrospiro[naphthalene-2(1H),5'-oxazolidin]-2'-one, trans,cis-; Spiro[naphthalene-2(1H),5-oxazolidin]-2-one, octahydro-, trans,cis-; 1-Azaspiro[4.5]decan-2-one, hexahydro-1-(2-oxoethyl)- (related structure); Spiro-oxazolidinone naphthalene derivative; 24192-11-8; SCHEMBL2383301; AKOS040759232
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is characterized and purified to meet exacting customer specifications, with purity typically exceeding 97% (by HPLC). Identity is confirmed via spectroscopic methods (NMR, IR, MS). A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profile is provided with each shipment to ensure traceability and compliance for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.