Description

Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Cis,cis- (8Ci) is a complex, stereochemically defined spirocyclic organic compound featuring a fused naphthalene-oxazolidinone structure. This unique molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate and a sophisticated building block for organic synthesis. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block for developing new generations of herbicides, fungicides, and insecticides with specific stereochemical activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex spirocyclic and polycyclic molecular frameworks.
• Material Science Precursor: Potential application in the synthesis of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, fused structure.
• Catalyst Ligand Development: The oxazolidinone moiety can be utilized to develop novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Cis,cis- (8Ci)
CAS No.	24192-09-4
Molecular Formula	C₁₄H₂₁NO₂
Molecular Weight	235.33 g/mol
Synonyms	Octahydrospiro[naphthalene-2(1H),5'-oxazolidin]-2'-one, cis,cis-; cis,cis-Octahydrospiro[naphthalene-2(1H),5'-oxazolidin]-2'-one; Spiro[naphthalene-2(1H),5'-oxazolidin]-2'-one, octahydro-, (2S,5R,8S,11R)-rel-; (2S,5R,8S,11R)-Octahydrospiro[naphthalene-2(1H),5'-oxazolidin]-2'-one; 24192-09-4; Spirocyclic oxazolidinone derivative.
EINECS	Contact for details

Quality Control

Our production of Spiro[Naphthalene-2(1H),5-Oxazolidin]-2-One, Octahydro-, Cis,cis- (8Ci) adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure consistent stereochemical integrity and high chemical purity suitable for critical R&D and scale-up processes. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.