Description

Methyl (2S)-2-{[(Benzyloxy)Carbonyl](Methyl)Amino}Propanoate CAS NO 24164-72-5 is a high-purity, chiral amino acid derivative used as a critical building block in advanced organic synthesis. Its primary value lies in its role as a protected intermediate for constructing complex peptides and peptidomimetics, enabling precise control over stereochemistry. This compound is essential for research and development in the pharmaceutical industry, particularly for medicinal chemists and process development teams working on active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs and complex bioactive molecules.
• Peptide Chemistry: Used for the controlled introduction of N-methylated amino acid residues into peptide chains, enhancing metabolic stability.
• Protease Inhibitor Development: Serves as a core building block in the research and production of inhibitors targeting specific enzymes.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the development of tool compounds and probes.
• Process Chemistry & Scale-up: Utilized in the development and optimization of scalable synthetic routes for GMP manufacturing.
• Academic & Industrial R&D: A valuable reagent for synthetic methodology development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	Methyl (2S)-2-{[(Benzyloxy)Carbonyl](Methyl)Amino}Propanoate
CAS No.	24164-72-5
Molecular Formula	C13H17NO4
Molecular Weight	251.28 g/mol
Synonyms	N-Cbz-N-Methyl-L-alanine methyl ester; Methyl N-[(benzyloxy)carbonyl]-N-methyl-L-alaninate; N-Carbobenzoxy-N-methyl-L-alanine methyl ester; (Z)-N-Methyl-L-alanine methyl ester; Cbz-N-Me-Ala-OMe; L-Alanine, N-[(phenylmethoxy)carbonyl]-N-methyl-, methyl ester; (S)-Methyl 2-((((benzyloxy)carbonyl)(methyl)amino)propanoate
EINECS	Contact for details

Quality Control

Our Methyl (2S)-2-{[(Benzyloxy)Carbonyl](Methyl)Amino}Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.