Description

Febrifugine CAS NO 24159-07-7 is a bioactive quinazolinone alkaloid known for its potent antimalarial properties. This compound is of significant interest in pharmaceutical research and development, particularly for the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of antiparasitic drugs and phytochemical studies.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of novel antimalarial and antiparasitic drug candidates.
• Biomedical Research: Used as a reference standard and active compound in pharmacological studies targeting *Plasmodium* species and other parasites.
• Natural Product Chemistry: Serves as a model compound in the study and synthesis of quinazolinone alkaloids derived from traditional medicinal plants like *Dichroa febrifuga*.
• Chemical Biology: Employed in mechanistic studies to investigate cellular pathways and validate biological targets related to fever and parasitic infections.
• Fine Chemical Synthesis: Utilized in advanced organic synthesis for creating analogs to explore structure-activity relationships (SAR).

Basic Information

Product Name	Febrifugine
CAS No.	24159-07-7
Molecular Formula	C16H19N3O3
Molecular Weight	301.34 g/mol
Synonyms	(-)-Febrifugine; β-Dichroine; Dichroine B; 3-[(2S,3R)-3-(3-Hydroxy-2-piperidinyl)-2-oxopropyl]-4(3H)-quinazolinone; Isofebrifugine (isomer); Chang Shan Alkaloid; NSC 32916
EINECS	Contact for details

Quality Control

Our Febrifugine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.