Description

Tms CAS NO 24144-92-1 is a highly volatile organosilicon compound, primarily recognized as a key reagent in organic synthesis and surface modification. Its core value lies in its ability to act as a versatile silylating agent, introducing the trimethylsilyl (TMS) protecting group to sensitive functional groups like alcohols and amines. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: Used as a protecting group reagent for hydroxyl and amino groups during the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the manufacture of pesticides and herbicides where silylation is required to control reactivity and improve product stability.
• Surface Derivatization for Chromatography: A critical reagent for modifying the surface of silica gel in the production of specialized HPLC columns and solid-phase extraction media.
• Polymer and Material Science: Utilized to introduce silyl groups into polymer chains or material surfaces, altering properties like hydrophobicity, adhesion, and thermal stability.
• Analytical Chemistry: Serves as a derivatization agent in Gas Chromatography (GC) and Mass Spectrometry (MS) to improve the volatility and detectability of polar compounds.
• Semiconductor and Electronics Manufacturing: Applied in chemical vapor deposition (CVD) processes and as a precursor for low-k dielectric materials in microelectronics.

Basic Information

Product Name	Tms CAS NO 24144-92-1
CAS No.	24144-92-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Trimethylsilyl reagent (TMS); Silylating agent 24144-92-1; TMS derivative; Organosilane reagent; Silicon protecting group reagent; (CH3)3Si- reagent; CAS 24144-92-1
EINECS	Contact for details

Quality Control

Our Tms CAS NO 24144-92-1 is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including purity assay and impurity profiling via techniques such as GC and NMR, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated place, ideally at temperatures between 2°C and 8°C. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture ingress and degradation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.