Description

3β-[[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Acetyl]Oxy]Androst-5-En-17-One is a specialized steroid derivative of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key synthetic intermediate in the creation of novel therapeutic agents, particularly those targeting hormone-related pathways. Pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers require this high-purity building block to support their discovery and process development programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of steroidal drugs and experimental therapeutics.
• Research Chemical: Used in academic and industrial laboratories for biochemical and pharmacological studies, particularly investigating steroid hormone action and modification.
• Drug Discovery: Employed in medicinal chemistry programs to develop new chemical entities (NCEs) with potential anti-cancer or endocrine-modulating properties, leveraging its nitrogen mustard functional group.
• Process Chemistry: Acts as a standardized starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and impurity profiling of related steroid compounds.

Basic Information

Product Name	3β-[[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Acetyl]Oxy]Androst-5-En-17-One
CAS No.	24141-90-0
Molecular Formula	C31H41Cl2NO3
Molecular Weight	546.57 g/mol
Synonyms	3β-[[[4-[Bis(2-chloroethyl)amino]phenyl]acetyl]oxy]androst-5-en-17-one; 3β-Hydroxyandrost-5-en-17-one 4-[bis(2-chloroethyl)amino]phenylacetate; Androst-5-en-17-one, 3-[[[4-[bis(2-chloroethyl)amino]phenyl]acetyl]oxy]-, (3β)-; Estradiol Nitrogen Mustard Conjugate (related class); Steroidal Nitrogen Mustard Derivative
EINECS	Contact for details

Quality Control

Our production of 3β-[[[4-[Bis(2-Chloroethyl)Amino]Phenyl]Acetyl]Oxy]Androst-5-En-17-One adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical characterization including HPLC for purity, NMR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all test results are provided to ensure traceability and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.