Description

Z-Thr-Ocho CAS NO 24127-06-8 is a protected amino acid derivative, specifically the benzyloxycarbonyl (Z or Cbz) protected form of threonine with a methyl ester (Ocho) group. This compound is a critical building block in peptide synthesis, offering orthogonal protection strategies essential for constructing complex peptides and bioactive molecules. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced organic synthesis and drug discovery programs.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of threonine residues into peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for the production of custom peptides and peptide mimetics.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of peptide-based therapeutics and APIs.
• Bioconjugation Chemistry: Employed to introduce threonine motifs into larger biomolecules or synthetic scaffolds.
• Chemical Biology Research: Utilized in the study of protein structure, function, and post-translational modifications.
• Protecting Group Strategy: The Z-group provides acid-labile protection, allowing for selective deprotection in multi-step syntheses.

Basic Information

Product Name	Z-Thr-Ocho
CAS No.	24127-06-8
Molecular Formula	C₁₃H₁₇NO₅
Molecular Weight	267.28 g/mol
Synonyms	N-Carbobenzyloxy-L-threonine methyl ester; Cbz-L-threonine methyl ester; Z-L-Thr-OMe; Nα-(Benzyloxycarbonyl)-L-threonine methyl ester; (2S,3R)-Methyl 2-(((benzyloxy)carbonyl)amino)-3-hydroxybutanoate; L-Threonine, N-[(phenylmethoxy)carbonyl]-, methyl ester; Z-Thr-OMe
EINECS	Contact for details

Quality Control

Our Z-Thr-Ocho is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing key parameters such as assay, enantiomeric purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.