Description

4-Isocyanato-1-(Trifluoroacetyl)Piperidine is a specialized, high-value organic building block that combines a reactive isocyanate group with a trifluoroacetyl-substituted piperidine ring. This unique bifunctional structure makes it a critical intermediate for synthesizing novel compounds with tailored properties, particularly in advanced material and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries who require precise molecular scaffolds to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel piperidine-based drug candidates, potentially for central nervous system (CNS) or metabolic disorder targets.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection, where the trifluoromethyl group can enhance biological activity and stability.
• Specialty Polymer & Resin Modifier: The isocyanate group enables incorporation into polyurethane chains or other polymers, imparting unique fluorinated characteristics for specialized coatings or materials.
• Ligand & Catalyst Development: Acts as a building block for creating complex ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for bioconjugation or as a scaffold in probe molecule development for studying biological systems.
• Advanced Material Research: Employed in R&D for creating novel fluorinated organic compounds with specific electronic or surface properties.

Basic Information

Product Name	4-Isocyanato-1-(Trifluoroacetyl)Piperidine
CAS No.	24095-40-7
Molecular Formula	C8H9F3N2O2
Molecular Weight	222.17 g/mol
Synonyms	1-(Trifluoroacetyl)-4-isocyanatopiperidine; 4-Isocyanato-1-(trifluoroacetyl)piperidine; 1-(Trifluoroacetyl)piperidin-4-yl isocyanate; Piperidine, 4-isocyanato-1-(trifluoroacetyl)-; 4-Isocyanato-1-piperidinyl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our production of 4-Isocyanato-1-(Trifluoroacetyl)Piperidine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maximize stability, given its moisture-sensitive (hygroscopic) nature. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.