Description

2-Bromo-1-(6-Chloropyridin-3-Yl)-Ethanone is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value proposition lies in its reactive bromoacetyl group adjacent to the chloropyridine ring, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Chemical Research & Development: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions for constructing complex heterocyclic systems.
• Material Science Precursor: Potential intermediate in the synthesis of functionalized ligands for catalysts or organic electronic materials.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Bromo-1-(6-Chloropyridin-3-Yl)-Ethanone
CAS No.	23794-13-0
Molecular Formula	C7H5BrClNO
Molecular Weight	234.48 g/mol
Synonyms	2-Bromo-1-(6-chloro-3-pyridinyl)ethanone; 2-Bromo-6'-chloro-3'-pyridyl methyl ketone; 1-(6-Chloropyridin-3-yl)-2-bromoethanone; 6-Chloro-3-pyridyl bromomethyl ketone; 2-Bromo-1-(6-chloro-pyridin-3-yl)-ethanone; α-Bromo-6-chloronicotinyl ketone; Ethanone, 2-bromo-1-(6-chloro-3-pyridinyl)-
EINECS	Contact for details

Quality Control

Every batch of our 2-Bromo-1-(6-Chloropyridin-3-Yl)-Ethanone undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and synthesis. Our quality management system ensures traceability and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.