Description

2-((2-Trifluoromethylphenylamino)Methylene)Malonic Acid Diethyl Ester is a high-value, specialized chemical intermediate featuring a unique trifluoromethyl-substituted aromatic amine structure. This compound is critical for synthesizing complex molecules where the introduction of fluorine atoms and a reactive malonate ester moiety is required. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom's ability to improve lipophilicity and target binding.
• Material Science Research: Serves as a precursor for creating specialized monomers or ligands used in the development of advanced polymers, coatings, or metal-organic frameworks (MOFs).
• Organic Synthesis & Methodology Development: Employed in academic and industrial R&D labs for studying novel condensation, cyclization, or fluorination reactions due to its reactive methylene malonate group.
• Fine Chemical Production: Acts as a versatile intermediate for manufacturing complex, high-value specialty chemicals used in electronics or performance materials.

Basic Information

Item	Details
Product Name	2-((2-Trifluoromethylphenylamino)Methylene)Malonic Acid Diethyl Ester
CAS No.	23779-94-4
Molecular Formula	C15H16F3NO4
Molecular Weight	331.29 g/mol
Synonyms	Diethyl 2-[(2-(trifluoromethyl)phenyl)imino]malonate; Diethyl (2-((2-Trifluoromethylphenyl)imino)malonate; 2-((2-Trifluoromethylphenyl)imino)malonic Acid Diethyl Ester; Ethyl 2-((2-(trifluoromethyl)phenyl)amino)methylene)malonate; (2-Trifluoromethylphenylimino)malonic Acid Diethyl Ester; Malonic acid, [(2-(trifluoromethyl)phenyl)imino]-, diethyl ester
EINECS	Contact for details

Quality Control

Every batch of our 2-((2-Trifluoromethylphenylamino)Methylene)Malonic Acid Diethyl Ester is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are designed to meet the exacting requirements of advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.