Description

D-Threono-1,4-Lactone is a high-purity chiral lactone, a key intermediate in organic synthesis and pharmaceutical manufacturing. Its value lies in its role as a versatile building block for the production of complex molecules, including nucleoside analogs, antiviral agents, and fine chemicals. This compound is essential for research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality chiral synthons.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of nucleoside-based antiviral drugs and other active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of complex organic molecules, including natural products and specialty chemicals requiring specific stereochemistry.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and enzymatic research.
• Agrochemical Development: Employed in the research and synthesis of novel, chiral agrochemicals and plant growth regulators.
• Cosmetic Ingredient Synthesis: Used as an intermediate for producing certain moisturizing agents and skin-conditioning compounds.

Basic Information

Product Name	D-Threono-1,4-Lactone
CAS No.	23732-41-4
Molecular Formula	C4H6O4
Molecular Weight	118.09 g/mol
Synonyms	D-Threonic acid γ-lactone; (3R,4S)-3,4-Dihydroxydihydro-2(3H)-furanone; D-(-)-Threono-1,4-lactone; D-Threonic acid 1,4-lactone; D-Threonolactone; 2(3H)-Furanone, 3,4-dihydroxydihydro-, (3R,4S)-; D-(-)-Threonolactone; Threono-1,4-lactone, D-
EINECS	Contact for details

Quality Control

Our D-Threono-1,4-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.