Description

2,3-o-Isopropylidene-2-C-Methyl-D-Ribonic-γ-Lactone is a high-purity, protected sugar lactone derivative that serves as a critical chiral building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures with precise stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in nucleoside chemistry and asymmetric synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of nucleoside analogs and antiviral/antitumor drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material for constructing stereodefined carbon frameworks.
• Agrochemical Research: Employed in the development of novel, biologically active compounds with specific stereochemical requirements.
• Carbohydrate Chemistry: Serves as a protected and functionalized sugar derivative for complex oligosaccharide and glycomimetic synthesis.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2,3-o-Isopropylidene-2-C-Methyl-D-Ribonic-γ-Lactone
CAS No.	23709-41-3
Molecular Formula	C9H14O5
Molecular Weight	202.20 g/mol
Synonyms	2,3-O-Isopropylidene-2-C-methyl-D-ribono-1,4-lactone; 2-C-Methyl-2,3-O-isopropylidene-D-ribono-γ-lactone; 2,3-O-Isopropylidene-2-C-methylribono-1,4-lactone; (3aR,5R,6S,6aR)-5-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol; D-Ribonic acid, 2-C-methyl-, γ-lactone, 2,3-O-isopropylidene-; Protected 2-C-methylribonolactone
EINECS	Contact for details

Quality Control

Our 2,3-o-Isopropylidene-2-C-Methyl-D-Ribonic-γ-Lactone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity standards suitable for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.