Description

4-[(Trimethylsilyl)Oxy]-1-Cyclohexanone is a valuable organosilicon-protected derivative of 1,4-cyclohexanedione, offering enhanced stability and solubility for advanced synthetic transformations. This compound serves as a crucial protected synthon and key intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing functionalized cyclohexane rings.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Acts as a protected 1,4-diketone equivalent in multi-step organic reactions, including alkylations, aldol condensations, and Michael additions.
• Material Science Precursor: Intermediate in the synthesis of specialty polymers, ligands for catalysis, and advanced organic materials.
• Asymmetric Synthesis: Chiral starting material or intermediate for the production of enantiomerically pure compounds.
• Cross-Coupling Reactions: Substrate for modern metal-catalyzed cross-coupling methodologies in complex molecule assembly.

Basic Information

Product Name	4-[(Trimethylsilyl)Oxy]-1-Cyclohexanone
CAS No.	23510-94-3
Molecular Formula	C9H18O2Si
Molecular Weight	186.32 g/mol
Synonyms	1-Cyclohexanone, 4-[(trimethylsilyl)oxy]-; 4-(Trimethylsiloxy)cyclohexanone; 4-(Trimethylsilyloxy)cyclohexanone; 4-Trimethylsiloxycyclohexanone; 4-O-Trimethylsilyl-1,4-cyclohexanedione mono-TMS enol ether; 4-Hydroxy-1-cyclohexanone trimethylsilyl ether; 1,4-Cyclohexanedione mono(trimethylsilyl) enol ether
EINECS	Contact for details

Quality Control

Our 4-[(Trimethylsilyl)Oxy]-1-Cyclohexanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.