Description

Methyl 2-Butynoate is a versatile alkyne ester building block used in advanced organic synthesis. Its high reactivity, particularly in cycloaddition and coupling reactions, makes it a valuable intermediate for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce acetylene functionality into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the production of active pharmaceutical ingredients (APIs), particularly those requiring alkyne moieties for further functionalization or as part of the core structure.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators where the acetylene unit contributes to biological activity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers and resins with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Employed in Huisgen cycloaddition (click chemistry), Sonogashira coupling, and other metal-catalyzed reactions to construct complex organic compounds.
• Flavor and Fragrance Industry: Acts as a precursor for synthesizing specific aroma compounds and flavoring agents.
• Research & Development: A critical reagent in academic and industrial R&D labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	Methyl 2-Butynoate
CAS No.	23326-27-4
Molecular Formula	C5H6O2
Molecular Weight	98.10 g/mol
Synonyms	2-Butynoic acid, methyl ester; Methyl but-2-ynoate; Methyl tetrolate; Tetrolic acid methyl ester; 2-Butynoic acid methyl ester; Methyl 2-butynoic acid ester; Methyl acetyleneacetate
EINECS	245-579-1

Quality Control

Our Methyl 2-Butynoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.420 - 1.430
Density (20°C)	0.95 - 0.98 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.