Description

3,5-Diindo-L-Tyrosine Methyl Ester is a specialized iodinated derivative of the amino acid tyrosine, serving as a crucial synthetic intermediate and research chemical. This compound matters for its role in the development of thyroid hormone analogs, radiopharmaceutical precursors, and biochemical probes due to its unique halogenated aromatic structure. It is primarily needed by pharmaceutical R&D laboratories, radiochemistry facilities, and academic institutions focused on endocrinology, molecular imaging, and organic synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of thyroid hormone analogs and related bioactive molecules.
• Radiopharmaceutical Precursor: Used in research for developing iodine-123 or iodine-131 labeled compounds for diagnostic imaging and therapy.
• Biochemical Research: Serves as a probe or substrate in enzymatic studies related to tyrosine metabolism and halogenation pathways.
• Organic Synthesis: Valuable intermediate for introducing iodinated tyrosine motifs into more complex peptide or small molecule architectures.
• Reference Standard: Employed as an analytical standard in HPLC or LC-MS methods for quality control and metabolic studies.

Basic Information

Product Name	3,5-Diindo-L-Tyrosine Methyl Ester
CAS No.	23277-41-0
Molecular Formula	C10H11I2NO3
Molecular Weight	446.01 g/mol
Synonyms	Methyl 3,5-diiodo-L-tyrosinate; L-Tyrosine, 3,5-diiodo-, methyl ester; Methyl (2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoate; 3,5-Diiodotyrosine methyl ester; DIITME; 3,5-Diiodo-L-tyrosine methyl ester
EINECS	Contact for details

Quality Control

Our 3,5-Diindo-L-Tyrosine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.