Description

Ethyl 6-(4-Bromophenyl)-2-Methylpyridine-3-Carboxylate is a high-purity, functionalized pyridine derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in pharmaceutical and agrochemical research and development. This compound is essential for chemists and manufacturers in the life sciences sector who require reliable, high-quality building blocks for drug discovery, process development, and the synthesis of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging the bioactivity of the bromophenyl-pyridine core structure.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in catalysis, such as in cross-coupling reactions, due to the presence of the bromine substituent.
• Material Science Precursor: Employed in the research and development of organic electronic materials, including organic light-emitting diodes (OLEDs) or charge-transport materials.
• Chemical Biology Probe Development: Utilized as a core structure for designing molecular probes and tool compounds to study biological processes and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 6-(4-Bromophenyl)-2-Methylpyridine-3-Carboxylate
CAS No.	23258-01-7
Molecular Formula	C15H14BrNO2
Molecular Weight	320.18 g/mol
Synonyms	Ethyl 6-(4-bromophenyl)-2-methylnicotinate; 3-Pyridinecarboxylic acid, 6-(4-bromophenyl)-2-methyl-, ethyl ester; 2-Methyl-6-(4-bromophenyl)nicotinic acid ethyl ester; 6-(4-Bromophenyl)-2-methylpyridine-3-carboxylic acid ethyl ester; Ethyl 6-(p-bromophenyl)-2-methylnicotinate; Ethyl 2-methyl-6-(4-bromophenyl)nicotinate; Aryl-substituted pyridine ester; Bromophenyl methylpyridine carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-(4-Bromophenyl)-2-Methylpyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.