Description

3-Isothiazolecarboxylic Acid Ethyl Ester is a versatile heterocyclic building block and ester derivative of isothiazole, prized for its role as a key synthetic intermediate in advanced organic synthesis. Its value lies in providing a functionalized isothiazole core, enabling the construction of complex molecules for research and industrial applications. This compound is primarily needed by pharmaceutical R&D teams, agrochemical scientists, and specialty chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialized polymers, ligands for catalysis, and other functional organic materials that incorporate the isothiazole heterocycle.
• Chemical Biology & Proteomics: Employed as a reactive handle or scaffold in the design of molecular probes, enzyme inhibitors, and bioconjugation tools.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	3-Isothiazolecarboxylic Acid Ethyl Ester
CAS No.	23244-32-8
Molecular Formula	C6H7NO2S
Molecular Weight	157.19 g/mol
Synonyms	Ethyl 3-Isothiazolecarboxylate; Ethyl Isothiazole-3-carboxylate; 3-Carbethoxyisothiazole; Isothiazole-3-carboxylic Acid Ethyl Ester; 1,2-Thiazole-3-carboxylic Acid, Ethyl Ester; 3-Isothiazolecarboxylic Acid, Ethyl Ester; Ethyl 1,2-Thiazole-3-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Isothiazolecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.