Description

Methyl 4-Isocyanatobenzoate is a versatile aromatic isocyanate ester, serving as a critical building block for introducing the isocyanate functional group into more complex molecular architectures. This compound is essential for synthesizing advanced materials and fine chemicals where precise molecular design is paramount. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for applications such as linker chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating amide and urea linkages in drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where it acts as a coupling agent.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for producing polyurethanes, polyureas, and other specialty polymers with tailored properties.
• Bioconjugation & Linker Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other bioconjugates, facilitating the attachment of payloads to targeting molecules.
• Material Science Research: A valuable precursor for creating novel organic frameworks, coatings, and adhesives in R&D settings.
• Chemical Derivatization: Used to introduce the isocyanate moiety into dyes, pigments, and other fine chemicals to alter solubility or reactivity.

Basic Information

Product Name	Methyl 4-Isocyanatobenzoate
CAS No.	23138-53-6
Molecular Formula	C9H7NO3
Molecular Weight	177.16 g/mol
Synonyms	4-Isocyanatobenzoic Acid Methyl Ester; Methyl p-Isocyanatobenzoate; Benzoic Acid, 4-Isocyanato-, Methyl Ester; Methyl 4-Isocyanato Benzoate; p-(Methoxycarbonyl)phenyl Isocyanate; Methyl Ester of 4-Isocyanatobenzoic Acid
EINECS	Contact for details

Quality Control

Our Methyl 4-Isocyanatobenzoate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), purity, and moisture content is provided with every shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.