Description

Methyl 4-Bromobicyclo[2.2.2]Octane-1-Carboxylate is a high-purity, functionalized bicyclic organic compound that serves as a versatile and valuable building block in advanced synthetic chemistry. Its rigid, three-dimensional bicyclo[2.2.2]octane scaffold, combined with reactive bromine and ester functional groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry, ligand synthesis, and the development of novel polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and other therapeutic areas requiring rigid, three-dimensional pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bicyclic structure can impart unique biological activity and environmental stability.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal stability, rigidity, and specific optical properties.
• Ligand & Catalyst Development: The bromine substituent allows for further functionalization via cross-coupling reactions, making it a precursor for sophisticated ligands used in asymmetric catalysis and organometallic chemistry.
• Academic & Industrial R&D: A valuable tool for synthetic methodology development and for studying structure-activity relationships (SAR) in various chemical contexts.

Basic Information

Item	Details
Product Name	Methyl 4-Bromobicyclo[2.2.2]Octane-1-Carboxylate
CAS No.	23062-51-3
Molecular Formula	C10H15BrO2
Molecular Weight	247.13 g/mol
Synonyms	Methyl 4-bromobicyclo[2.2.2]octane-1-carboxylate; 4-Bromobicyclo[2.2.2]octane-1-carboxylic acid methyl ester; 1-Carbomethoxy-4-bromobicyclo[2.2.2]octane; Methyl 4-bromoadamantane-1-carboxylate (common misnomer); Bicyclo[2.2.2]octane-1-carboxylic acid, 4-bromo-, methyl ester; 4-Bromo-1-(methoxycarbonyl)bicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our Methyl 4-Bromobicyclo[2.2.2]Octane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the consistency and reliability required for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.