Description

(S)-1-Acetyl-Pyrrolidine-2-Carboxylic Acid Ethyl Ester is a high-value chiral intermediate and building block of significant importance in modern synthetic chemistry. Its core value lies in its stereochemical purity, which is essential for the development of enantiomerically pure pharmaceuticals and bioactive compounds. This product is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in protease inhibitor and neurological drug research.
• Asymmetric Synthesis: Serves as a versatile building block in stereoselective reactions, including chiral auxiliary applications and the construction of complex molecular architectures.
• Peptidomimetics Research: Used in the design and synthesis of peptidomimetic compounds, which are crucial for developing novel therapeutics with improved metabolic stability.
• Agrochemical Development: Employed as an intermediate in the synthesis of chiral agrochemicals, where specific stereochemistry can influence biological activity and environmental safety.
• Catalyst and Ligand Synthesis: Acts as a precursor for the development of novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic and R&D Laboratories: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(S)-1-Acetyl-Pyrrolidine-2-Carboxylic Acid Ethyl Ester
CAS No.	23037-82-3
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	L-Proline, 1-acetyl-, ethyl ester; Ethyl (2S)-1-acetyl-2-pyrrolidinecarboxylate; (S)-(-)-1-Acetyl-2-pyrrolidinecarboxylic Acid Ethyl Ester; (S)-1-Acetyl-2-pyrrolidinecarboxylic Acid Ethyl Ester; Ethyl 1-acetyl-L-prolinate; L-Proline ethyl ester, N-acetyl-; N-Acetyl-L-proline ethyl ester; N-Acetylproline ethyl ester
EINECS	Contact for details

Quality Control

Our (S)-1-Acetyl-Pyrrolidine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent industry standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.