Description

(E)-1-Phenyl-3-(4-Bromophenyl)-2-Propene-1-One is a high-purity, light-sensitive chalcone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for the development of novel pharmaceuticals and functional materials. Industrial researchers and process chemists in pharmaceutical R&D, agrochemical development, and material science laboratories need this precise intermediate for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its chalcone core for bioactive molecule design.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probe: Utilized as a scaffold for creating fluorescent probes or enzyme inhibitors to study biological pathways.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, Michael additions, and cyclization reactions to create complex heterocyclic compounds.
• Academic & Institutional Research: Essential for universities and research institutes conducting studies in medicinal chemistry and synthetic methodology.

Basic Information

Product Name	(E)-1-Phenyl-3-(4-Bromophenyl)-2-Propene-1-One
CAS No.	22966-09-2
Molecular Formula	C15H11BrO
Molecular Weight	287.15 g/mol
Synonyms	(E)-3-(4-Bromophenyl)-1-phenylprop-2-en-1-one; 4-Bromochalcone; 3-(4-Bromophenyl)-1-phenyl-2-propen-1-one; (E)-1-Phenyl-3-(p-bromophenyl)-2-propen-1-one; p-Bromochalcone; NSC 403914; (E)-3-(4-Bromophenyl)-1-phenylprop-2-en-1-one; 2-Propen-1-one, 3-(4-bromophenyl)-1-phenyl-, (E)-
EINECS	Contact for details

Quality Control

Our (E)-1-Phenyl-3-(4-Bromophenyl)-2-Propene-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.