Description

[4-[Bis(2-Chloroethyl)Amino]Phenyl] 4-Methoxybenzoate is a specialized nitrogen mustard derivative ester, a compound of significant interest in advanced chemical synthesis. Its molecular architecture, featuring a bifunctional alkylating moiety, makes it a valuable intermediate for research and development in targeted therapeutic areas. This product is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules and prodrug systems.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of potential alkylating chemotherapeutic agents and prodrugs.
• Biochemical Research: Used in studies investigating DNA alkylation, cross-linking mechanisms, and structure-activity relationships (SAR) of nitrogen mustard compounds.
• Anticancer Agent Development: Serves as a precursor or model compound for synthesizing novel targeted therapies designed to minimize systemic toxicity.
• Prodrug Synthesis: Employed in creating inactive prodrug forms that can be selectively activated in specific physiological environments.
• Chemical Biology Tool: Utilized as a molecular probe to study cellular pathways and protein interactions involving alkylation events.
• Fine Chemical Synthesis: Intermediate for creating complex, high-value specialty chemicals with specific biological or material properties.

Basic Information

Product Name	[4-[Bis(2-Chloroethyl)Amino]Phenyl] 4-Methoxybenzoate
CAS No.	22953-57-7
Molecular Formula	C20H23Cl2NO3
Molecular Weight	396.31 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenyl 4-methoxybenzoate; p-[Bis(2-chloroethyl)amino]phenyl p-anisate; 4-Methoxybenzoic acid 4-[bis(2-chloroethyl)amino]phenyl ester; Phenyl 4-methoxybenzoate nitrogen mustard derivative; Chlorambucil p-anisate analog; Nor-HN2 p-anisate ester
EINECS	Contact for details

Quality Control

Every batch of [4-[Bis(2-Chloroethyl)Amino]Phenyl] 4-Methoxybenzoate is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.