Description

Phenol, p-(Bis(2-Chloroethyl)Amino)-, p-Fluorobenzoate is a specialized nitrogen mustard derivative, a class of compounds known for their alkylating properties. This compound is of significant interest in advanced pharmaceutical research and development, particularly in the synthesis of targeted therapeutic agents. It serves as a critical intermediate for researchers and manufacturers in the oncology and medicinal chemistry sectors, where precise molecular architecture is paramount for developing novel treatments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel alkylating prodrugs.
• Bioconjugation: Serves as a linker or payload in antibody-drug conjugate (ADC) development for targeted drug delivery.
• Biochemical Tool Compound: Employed in laboratory research to study DNA alkylation mechanisms and cellular apoptosis pathways.
• Preclinical Development: Utilized in the synthesis of candidate molecules for pharmacokinetic and efficacy studies.

Basic Information

Product Name	Phenol, p-(Bis(2-Chloroethyl)Amino)-, p-Fluorobenzoate
CAS No.	22953-56-6
Molecular Formula	C19H20Cl2FNO3
Molecular Weight	400.27 g/mol
Synonyms	p-[Bis(2-chloroethyl)amino]phenyl p-fluorobenzoate; 4-[Bis(2-chloroethyl)amino]phenyl 4-fluorobenzoate; Phenyl 4-fluorobenzoate, 4'-[bis(2-chloroethyl)amino]-; Fluorobenzoate nitrogen mustard; 4-Fluorobenzoic acid 4-[bis(2-chloroethyl)amino]phenyl ester; AN-207; Triptorelin p-fluorobenzoate mustard
EINECS	Contact for details

Quality Control

Our Phenol, p-(Bis(2-Chloroethyl)Amino)-, p-Fluorobenzoate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.