Description

p-[Bis(2-Chloroethyl)Amino]Phenyl=p-Bromobenzoate is a specialized nitrogen mustard derivative, a class of compounds known for their alkylating properties. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in the development of novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of potential alkylating chemotherapeutic agents and targeted therapies.
• Biochemical Research: Used as a model compound in studies of DNA alkylation, cytotoxicity mechanisms, and structure-activity relationships (SAR).
• Antineoplastic Agent Development: Serves as a core scaffold for modifying and developing new nitrogen mustard analogs with improved efficacy and reduced side effects.
• Organic Synthesis Building Block: Utilized in constructing complex molecules for medicinal chemistry due to its reactive chloroethyl and ester functional groups.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	p-[Bis(2-Chloroethyl)Amino]Phenyl=p-Bromobenzoate
CAS No.	22953-53-3
Molecular Formula	C19H20BrCl2NO2
Molecular Weight	445.18 g/mol
Synonyms	4-[Bis(2-chloroethyl)amino]phenyl 4-bromobenzoate; p-[Bis(2-chloroethyl)amino]phenyl p-bromobenzoate; 4-Bromobenzoic acid 4-[bis(2-chloroethyl)amino]phenyl ester; Phenyl-p-bromobenzoate nitrogen mustard; Mustard p-bromobenzoate derivative; NSC 176319; 22953-53-3
EINECS	Contact for details

Quality Control

Our p-[Bis(2-Chloroethyl)Amino]Phenyl=p-Bromobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation (IR, NMR), and specific impurity profiling. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. This compound is moisture-sensitive; handle and store under an inert atmosphere such as nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.