Description

δ-5(6)-Norethindrone is a key pharmaceutical intermediate and a derivative of the synthetic progestin norethisterone. This compound is of significant importance in the research and development of steroid-based active pharmaceutical ingredients (APIs) and hormonal therapies. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the synthesis of advanced steroid molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of norethisterone and related progestin-based APIs.
• Steroid Research: Used as a reference standard and starting material in academic and industrial research focused on steroid chemistry and pharmacology.
• Hormone Analog Development: Serves as a precursor for the development of novel hormone analogs with potential therapeutic applications.
• Process Chemistry: Employed in the development and optimization of synthetic routes for complex steroid molecules within GMP manufacturing environments.

Basic Information

Product Name	δ-5(6)-Norethindrone
CAS No.	22933-71-7
Molecular Formula	C₂₀H₂₆O₂
Molecular Weight	298.42 g/mol
Synonyms	19-Nor-17α-pregn-5(6)-en-20-yn-3-one, 17β-ol; 17β-Hydroxy-19-nor-17α-pregn-5(6)-en-20-yn-3-one; δ5(6)-Norethindrone; δ5(6)-Norethisterone; 5(6)-Dehydronorethindrone; 5(6)-Dehydronorethisterone; 19-Norpregn-5(6)-en-20-yn-3-one, 17β-hydroxy-, (17α)-
EINECS	Contact for details

Quality Control

Our δ-5(6)-Norethindrone is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.