Description

4-Chloro-2-Iodopyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chlorine and iodine substituents, makes it a highly valuable intermediate for constructing complex molecules through cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create new bioactive compounds.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi coupling reactions due to the reactive iodine atom, facilitating carbon-carbon bond formation.
• Ligand and Catalyst Development: Employed in the preparation of novel nitrogen-containing ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical research and diagnostics.

Basic Information

Product Name	4-Chloro-2-Iodopyridine
CAS No.	22918-03-2
Molecular Formula	C5H3ClIN
Molecular Weight	239.44 g/mol
Synonyms	2-Iodo-4-chloropyridine; 4-Chloro-2-iodopyridine; 4-Chloro-2-iodo-pyridine; 2-Iodo-4-chloro-pyridine; Pyridine, 4-chloro-2-iodo-; 22918-03-2; 4-Chloro-2-iodo pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.