Description

Cyclopropanecarboxylic Acid, 2-Nitro-, Methyl Ester, trans- (8Ci) is a specialized organic compound featuring a nitro-substituted cyclopropane ring, serving as a valuable chiral building block and intermediate in advanced synthetic chemistry. Its rigid, strained cyclopropane structure and functional groups make it a critical precursor for constructing complex molecules with specific stereochemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as for advanced material science applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in constructing constrained ring systems.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cyclopropane moiety contributes to biological activity.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry for creating complex, stereodefined molecular architectures.
• Material Science Research: Acts as a monomer or precursor for developing specialized polymers and advanced functional materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-Nitro-, Methyl Ester, trans- (8Ci)
CAS No.	22882-45-7
Molecular Formula	C6H9NO4
Molecular Weight	159.14 g/mol
Synonyms	trans-2-Nitrocyclopropanecarboxylic Acid Methyl Ester; Methyl trans-2-Nitrocyclopropanecarboxylate; trans-Methyl 2-Nitrocyclopropanecarboxylate; (1R,2S)-rel-2-Nitrocyclopropanecarboxylic Acid Methyl Ester; (1S,2R)-rel-2-Nitrocyclopropanecarboxylic Acid Methyl Ester; 2-Nitrocyclopropanecarboxylic Acid Methyl Ester, trans-; NSC 163044
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-Nitro-, Methyl Ester, trans- (8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from direct light. Due to its potential sensitivity, it is recommended to store under an inert atmosphere for long-term preservation and to minimize the risk of degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.