Description

(2S,3R)-5-Methoxy-2-(((4-Methylbenzoyl)Oxy)Methyl)-Tetrahydrofuran-3-Yl 4-Methylbenzoate is a high-purity, stereochemically defined chemical intermediate of significant interest in advanced organic synthesis. Its value lies in its role as a key chiral building block for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents, particularly for complex targets.
• Agrochemical Synthesis: Used in the synthesis of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new chiral catalysts.
• Process Chemistry Development: Utilized for scaling up synthetic routes in pilot plants and optimizing manufacturing processes for chiral molecules.
• Academic & Institutional Research: A valuable tool for synthetic organic chemists in universities and R&D labs exploring new reaction methodologies.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(2S,3R)-5-Methoxy-2-(((4-Methylbenzoyl)Oxy)Methyl)-Tetrahydrofuran-3-Yl 4-Methylbenzoate
CAS No.	22837-37-2
Molecular Formula	C22H24O6
Molecular Weight	384.42 g/mol
Synonyms	5-Methoxy-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate; (2S,3R)-Tetrahydro-5-methoxy-2-[[(4-methylbenzoyl)oxy]methyl]-3-furanyl 4-methylbenzoate; 2(S),3(R)-5-Methoxy-2-(((4-Methylbenzoyl)Oxy)Methyl)-Tetrahydrofuran-3-Yl 4-Methylbenzoate; p-Toluic acid, 5-methoxy-2-(((4-methylbenzoyl)oxy)methyl)tetrahydro-3-furanyl ester, (2S,3R)-; Chiral furan derivative; Ditolyl furan ester intermediate; (2S,3R)-configured toluate ester.
EINECS	Contact for details

Quality Control

Our (2S,3R)-5-Methoxy-2-(((4-Methylbenzoyl)Oxy)Methyl)-Tetrahydrofuran-3-Yl 4-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and atmospheric contaminants. Store away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S,3R) isomer
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.