Description

Dodecyl 5-Oxo-L-Prolinate is a high-purity specialty ester derived from L-proline, designed for advanced formulation and synthesis. This compound is valued for its unique amphiphilic structure, which combines a lipophilic dodecyl chain with a hydrophilic pyrrolidone-derived head group, making it an effective intermediate and functional additive. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, cosmetic, and specialty chemical sectors for applications requiring controlled release, surface modification, or as a building block for novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of prodrugs and active pharmaceutical ingredients (APIs) with enhanced lipophilicity and bioavailability.
• Cosmetic & Personal Care Formulations: Acts as a skin-conditioning agent, emollient, or penetration enhancer in creams, lotions, and serums.
• Specialty Surfactants & Emulsifiers: Utilized in the synthesis of novel non-ionic surfactants for niche industrial and agrochemical applications.
• Polymer & Material Science: Employed as a monomer or modifying agent to impart specific functional properties to polymers.
• Research & Development: Used in academic and industrial R&D for studying ester prodrug strategies, membrane interactions, and novel chemical entities.
• Lubricant & Functional Fluid Additive: Functions as a high-performance additive to modify viscosity and surface properties in specialty lubricants.

Basic Information

Product Name	Dodecyl 5-Oxo-L-Prolinate
CAS No.	22794-26-9
Molecular Formula	C₁₇H₃₁NO₃
Molecular Weight	297.44 g/mol
Synonyms	L-Proline, 5-oxo-, dodecyl ester; Dodecyl L-pyroglutamate; Dodecyl (S)-5-oxopyrrolidine-2-carboxylate; Lauryl 5-oxo-L-prolinate; 5-Oxo-L-proline dodecyl ester; Lauryl pyroglutamate; (S)-Dodecyl 5-oxopyrrolidine-2-carboxylate; N/A
EINECS	Contact for details

Quality Control

Our Dodecyl 5-Oxo-L-Prolinate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) documenting all critical parameters are provided and can be tailored to meet specific customer or regulatory standards, including those for research and cGMP-guided applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.