Description

Dimethyl (R)-(+)-Methylsuccinate is a high-purity chiral ester derivative of methylsuccinic acid, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its enantiomeric purity, which is essential for producing optically active compounds with high stereoselectivity. This product is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active pharmaceutical ingredients (APIs), fine chemicals, and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides, herbicides, and plant growth regulators where specific stereochemistry is required for bioactivity.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in perfumery, flavorings, and advanced material precursors.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in the development and testing of new asymmetric catalytic methodologies.
• Polymer Chemistry: Can be utilized as a monomer or co-monomer for synthesizing specialized polyesters with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development for scale-up.

Basic Information

Product Name	Dimethyl (R)-(+)-Methylsuccinate
CAS No.	22644-27-5
Molecular Formula	C7H12O4
Molecular Weight	160.17 g/mol
Synonyms	(R)-(+)-Dimethyl 2-Methylsuccinate; (R)-Dimethyl Methylsuccinate; (R)-(+)-2-Methylbutanedioic Acid Dimethyl Ester; (R)-1,4-Dimethoxy-1,4-dioxobutan-2-ane; Methyl (R)-(+)-Methylsuccinate; (R)-Methylsuccinic Acid Dimethyl Ester; (2R)-2-Methylbutanedioic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl (R)-(+)-Methylsuccinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC or GC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing specific purity, enantiomeric excess (ee), and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Specific Rotation [α]	+15° to +20° (c=1 in CHCl3)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.