Description

cis-Diethylstilbestrol is a synthetic, non-steroidal estrogen and a geometric isomer of diethylstilbestrol (DES). This compound is significant for its potent estrogenic activity and serves as a critical reference standard and research chemical in endocrinology and pharmacology. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions studying hormone action, receptor binding, and the historical context of estrogenic compounds.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for the quality control and assay validation of related pharmaceutical products and in regulatory testing.
• Biochemical Research: Employed in studies of estrogen receptor (ER) binding affinity, mechanism of action, and structure-activity relationships (SAR) of synthetic estrogens.
• Analytical Chemistry: Serves as an analytical standard in methods like HPLC, LC-MS, and GC-MS for the identification and quantification of DES and its isomers in various matrices.
• Veterinary Science Research: Applied in historical and comparative research on the use of estrogens in animal growth promotion.
• Toxicology Studies: Utilized as a model compound in research investigating the endocrine-disrupting effects and long-term toxicity of synthetic hormones.

Basic Information

Product Name	cis-Diethylstilbestrol
CAS No.	22610-99-7
Molecular Formula	C18H20O2
Molecular Weight	268.35 g/mol
Synonyms	(Z)-Diethylstilbestrol; (E)-Diethylstilbestrol (trans-isomer); DES; Stilbestrol; 4,4'-(1,2-Diethyl-1,2-ethenediyl)bisphenol; alpha,alpha'-Diethyl-4,4'-stilbenediol; cis-DES; (Z)-4,4'-(1,2-Diethyl-1,2-ethenediyl)diphenol
EINECS	Contact for details

Quality Control

Our cis-Diethylstilbestrol is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing results for assay, related substances, and identification is provided to guarantee the material meets your research and analytical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
trans-Diethylstilbestrol	≤1.0%
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.