Description

Trimethyl-[(3E)-4-Trimethylsilylbuta-1,3-Dien-2-Yl]Silane is a specialized organosilicon compound featuring a conjugated diene system protected by silyl groups. This unique structure makes it a valuable highly reactive intermediate and building block in advanced organic synthesis. It is primarily used by R&D chemists and process development scientists in the pharmaceutical and advanced materials sectors for constructing complex molecular architectures, including natural products and functional polymers.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs), particularly in cycloaddition and cross-coupling reactions.
• Precursor for Specialty Polymers and Materials: Used in the development of novel silicon-containing polymers, dendrimers, and advanced materials with tailored electronic or mechanical properties.
• Reagent in Organic Methodology Development: Employed in academic and industrial research for developing new synthetic methodologies, such as Diels-Alder reactions and catalytic transformations.
• Agrochemical Intermediate: Acts as a synthon for creating novel, high-performance active ingredients for crop protection products.
• Ligand and Catalyst Modification: Utilized to synthesize novel organometallic complexes and ligands for asymmetric catalysis.

Basic Information

Product Name	Trimethyl-[(3E)-4-Trimethylsilylbuta-1,3-Dien-2-Yl]Silane
CAS No.	22500-95-4
Molecular Formula	C10H22Si2
Molecular Weight	198.45 g/mol
Synonyms	1,1,1,4,4,4-Hexamethyl-2-(trimethylsilyl)-2-silabuta-1,3-diene; (3E)-1,1,1,4,4,4-Hexamethyl-2-(trimethylsilyl)-2-silabuta-1,3-diene; 2-Trimethylsilyl-1,3-butadiene-2-yltrimethylsilane; 2-Trimethylsilyl-1-trimethylsilyl-1,3-butadiene; (E)-1,1,1,4,4,4-Hexamethyl-2-(trimethylsilyl)-2-silabuta-1,3-diene; TMS-Protected Butadiene Derivative
EINECS	Contact for details

Quality Control

Our Trimethyl-[(3E)-4-Trimethylsilylbuta-1,3-Dien-2-Yl]Silane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and HPLC, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and highly volatile nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95.0%
Isomeric Purity (GC)	≥ 98.0% (E-isomer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.