Description

Hydroxocobalamin Acetate is a stable, crystalline acetate salt form of hydroxocobalamin, a vital form of Vitamin B12. This high-purity compound is essential for applications requiring a reliable and bioavailable source of cobalamin, offering superior stability compared to the hydrochloride form. It is a critical raw material for the pharmaceutical, nutraceutical, and research sectors, where precise quality and consistent performance are paramount.

Application

• Pharmaceutical Formulations: Primary active ingredient in injectable and oral treatments for Vitamin B12 deficiency (e.g., pernicious anemia, neurological disorders).
• Nutraceutical & Dietary Supplements: Used in high-quality vitamin B-complex formulations, multivitamins, and standalone B12 supplements for enhanced bioavailability.
• Clinical & Diagnostic Reagents: Serves as a standard and reagent in clinical chemistry assays and diagnostic kits for B12 level determination.
• Biochemical Research: Essential cofactor in cell culture media and enzymatic studies investigating cobalamin-dependent metabolic pathways.
• Veterinary Medicine: Incorporated into animal health products for the treatment and prevention of B12 deficiencies in livestock and pets.
• Food & Beverage Fortification: Used for the nutritional fortification of foods, such as cereals, plant-based milk alternatives, and energy drinks.

Basic Information

Item	Details
Product Name	Hydroxocobalamin Acetate
CAS No.	22465-48-1
Molecular Formula	C66H90CoN13O15P • xC2H4O2
Molecular Weight	1346.37 g/mol (base)
Synonyms	Vitamin B12a Acetate; Hydroxocobalamin Acetate Salt; α-(5,6-Dimethylbenzimidazolyl)hydroxocobamide Acetate; Cobinamide Acetate; Hydroxocobalamin Monoacetate; Hydroxocobalamin Acetate Complex; Aquocobalamin Acetate; B12 Acetate
EINECS	Contact for details

Quality Control

Our Hydroxocobalamin Acetate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical and nutritional applications. A comprehensive Certificate of Analysis (COA) detailing identity, potency, purity, and related substances is provided with every shipment. We can supply material compliant with relevant pharmacopeial monographs (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	Dark red crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	≥ 96.0% (on anhydrous basis)
Water (Karl Fischer)	≤ 8.0 %
Related Substances (HPLC)	Total impurities ≤ 4.0%
Specific Rotation	Contact for details
Residue on Ignition	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.