Description

2-Methoxyethinyl Estradiol is a high-purity synthetic steroid compound, a derivative of ethinyl estradiol. This specialized intermediate is critical for pharmaceutical research and development, offering a key building block for advanced therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel steroid-based drugs and detailed biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel steroidal pharmaceuticals.
• Biochemical Research: Used as a reference standard or active compound in hormonal and metabolic pathway studies.
• API Development: Employed in the synthesis and process optimization of active pharmaceutical ingredients (APIs) for hormonal therapies.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for investigative chemistry and pharmacology projects.
• Method Development: Acts as an analytical standard for developing and validating chromatographic (e.g., HPLC) and spectroscopic assay methods.

Basic Information

Product Name	2-Methoxyethinyl Estradiol
CAS No.	22415-44-7
Molecular Formula	C21H26O3
Molecular Weight	326.43 g/mol
Synonyms	2-Methoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol; 2-Methoxyethynylestradiol; 17α-Ethynyl-2-methoxyestra-1,3,5(10)-triene-3,17β-diol; 2-Methoxy-17α-ethynylestradiol; 2-Methoxy EE2; 2-Methoxy Ethinyl Estradiol
EINECS	Contact for details

Quality Control

Our 2-Methoxyethinyl Estradiol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) standards where applicable, and specifications can be aligned with client requirements for advanced pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.