Description

Octadecanedioic Acid 1-Methyl 18-(Trimethylsilyl) Ester is a high-purity, functionalized long-chain dicarboxylic acid derivative. This compound is valued for its role as a versatile synthetic intermediate and protecting group in advanced organic synthesis. It is primarily needed by research and development laboratories, pharmaceutical manufacturers, and specialty chemical producers working on complex molecule construction, polymer modification, and surface chemistry applications.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, particularly those requiring long-chain hydrophobic segments or specific silyl-protected functionalities.
• Polymer Science: Used as a monomer or co-monomer for modifying polyester and polyamide properties, introducing silicon-containing groups to alter surface characteristics, thermal stability, or flexibility.
• Organic Synthesis: Acts as a protected form of octadecanedioic acid, enabling selective reactions at the free methyl ester group while the trimethylsilyl ester remains inert.
• Surface Modification Agent: Employed in the creation of self-assembled monolayers (SAMs) or coatings to impart specific hydrophobic or release properties to surfaces.
• Lubricant & Grease Additive: Functions as a precursor for synthesizing high-performance ester-based lubricants and additives.
• Material Science Research: Utilized in developing novel dendritic polymers, liquid crystals, and other advanced materials with tailored molecular architectures.

Basic Information

Product Name	Octadecanedioic Acid 1-Methyl 18-(Trimethylsilyl) Ester
CAS No.	22396-28-7
Molecular Formula	C22H44O4Si
Molecular Weight	400.68 g/mol
Synonyms	1-Methyl 18-(trimethylsilyl) octadecanedioate; Methyl 18-(trimethylsilyl)octadecanedioate; Octadecanedioic acid, 1-methyl 18-(trimethylsilyl) ester; 18-(Trimethylsilyl)octadecanedioic acid methyl ester; TMS-protected octadecanedioic acid monomethyl ester; Methyl hydrogen octadecanedioate TMS ester
EINECS	Contact for details

Quality Control

Our Octadecanedioic Acid 1-Methyl 18-(Trimethylsilyl) Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.