Description

12-(Trimethylsilyloxy)Octadecanoic Acid Trimethylsilyl Ester is a high-purity, fully silylated derivative of stearic acid, designed for advanced synthetic and analytical applications. This compound is valued for its enhanced volatility and stability, making it a critical reagent in processes requiring precise derivatization. It is primarily utilized by research chemists and quality control laboratories in the pharmaceutical, biotechnology, and specialty chemical industries for gas chromatography and mass spectrometry analysis.

Application

• Gas Chromatography (GC) and GC-MS Analysis: Used as a derivatization agent to increase the volatility and thermal stability of carboxylic acids and other polar compounds for accurate analytical separation and detection.
• Pharmaceutical Intermediate: Serves as a protected synthetic intermediate in the multi-step synthesis of complex organic molecules, including active pharmaceutical ingredients (APIs).
• Polymer and Material Science: Acts as a surface-modifying agent or a monomer precursor in the development of specialized silicone-based polymers and coatings.
• Biochemical Research: Employed in lipidomics and metabolomics studies for the derivatization and analysis of fatty acids and related metabolites.
• Reference Standard: Supplied as a high-purity certified reference material (CRM) for analytical method development, validation, and quality assurance protocols.

Basic Information

Product Name	12-(Trimethylsilyloxy)Octadecanoic Acid Trimethylsilyl Ester
CAS No.	22396-22-1
Molecular Formula	C24H52O3Si2
Molecular Weight	444.85 g/mol
Synonyms	Stearic Acid, 12-(Trimethylsilyloxy)-, Trimethylsilyl Ester; 12-Hydroxystearic Acid Bis(trimethylsilyl) Ether; 12-TMS-O-stearic Acid TMS Ester; Bis(trimethylsilyl) 12-(Trimethylsilyloxy)octadecanoate; 12-(Trimethylsilyloxy)stearic Acid Trimethylsilyl Ester; Octadecanoic Acid, 12-(Trimethylsilyloxy)-, Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our 12-(Trimethylsilyloxy)Octadecanoic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial applications. A Certificate of Analysis (COA) detailing purity, assay results, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.