Description

2-Nitro-4'-Methoxychalcone is a high-purity synthetic organic compound belonging to the chalcone class, characterized by its distinct nitro and methoxy functional groups. This compound serves as a versatile and critical pharmaceutical intermediate and research chemical for the development of novel bioactive molecules. It is primarily utilized by R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for anti-inflammatory, anticancer, and antimicrobial agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Organic Synthesis: Serves as a precursor for synthesizing more complex heterocyclic compounds like pyrazolines and flavones.
• Material Science Research: Investigated for its optical properties and potential application in the development of organic semiconductors or non-linear optical materials.
• Biochemical Tool Compound: Used in vitro to study specific biological pathways and enzyme interactions.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Nitro-4'-Methoxychalcone
CAS No.	22396-06-1
Molecular Formula	C₁₇H₁₅NO₄
Molecular Weight	297.31 g/mol
Synonyms	(E)-1-(2-Nitrophenyl)-3-(4-methoxyphenyl)prop-2-en-1-one; 2-Nitro-4'-methoxychalcone; 3-(4-Methoxyphenyl)-1-(2-nitrophenyl)-2-propen-1-one; 1-(2-Nitrophenyl)-3-(4-methoxyphenyl)-2-propen-1-one; 4'-Methoxy-2-nitrochalcone; NSC 403697; Chalcone, 2-nitro-4'-methoxy-
EINECS	Contact for details

Quality Control

Our 2-Nitro-4'-Methoxychalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.