Description

Dl-Biotin CAS NO 22377-59-9 is a synthetic, racemic form of the essential water-soluble B-vitamin, biotin (Vitamin B7 or Vitamin H). This high-purity compound is critical for supporting metabolic functions as a coenzyme for carboxylase enzymes. It serves as a vital raw material for manufacturers in the pharmaceutical, nutraceutical, and animal feed industries, where consistent quality and reliable supply are paramount for product formulation.

Application

• Pharmaceutical Formulations: Used in the production of vitamin supplements and injectable solutions to address biotin deficiency.
• Dietary Supplements & Fortified Foods: A key ingredient in multivitamin tablets, capsules, and functional foods for nutritional enhancement.
• Animal Nutrition (Feed Premixes): Incorporated into poultry, swine, and aquaculture feed to promote healthy growth, skin integrity, and hoof/horn quality.
• Cosmetic & Personal Care: Utilized in hair care and skin care products for its purported benefits in strengthening hair and nails and improving skin health.
• Biochemical Research: Serves as a standard and reagent in microbiological assays and metabolic pathway studies.
• Cell Culture Media: An essential growth factor component in specialized media formulations for biotechnology applications.

Basic Information

Product Name	Dl-Biotin
CAS No.	22377-59-9
Molecular Formula	C10H16N2O3S
Molecular Weight	244.31 g/mol
Synonyms	Racemic Biotin; (+/-)-Biotin; Vitamin B7 (racemic); Vitamin H (racemic); D,L-Biotin; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic Acid (racemate); Coenzyme R (racemic); cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric Acid (racemate)
EINECS	244-933-6

Quality Control

Our Dl-Biotin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for assay and related substances, to ensure it meets high-purity standards suitable for pharmaceutical and nutritional applications. Certificates of Analysis (COA) documenting compliance with relevant specifications (including in-process references to USP, EP, or FCC monographs) are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed after opening to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.0% - 101.0%
Specific Rotation	-0.10° to +0.10° (c=1 in 0.1N NaOH)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.